If you or someone you know is dealing with depression, you might wonder whether medication or talking therapy works better. This study looked at young people with depression and anxiety, comparing those who took an antidepressant (called an SSRI) alone versus those who combined it with cognitive behavioural therapy (CBT) — a type of talk therapy that helps you notice and change unhelpful thinking patterns. The combo worked faster overall, with real improvement by four weeks. But here's the interesting bit: CBT's extra benefit over medication alone didn't really show up until week twelve. So the talk therapy part takes longer to kick in, even though it's worth the wait. Younger people with milder symptoms and depression (rather than anxiety) tended to improve fastest, while boys, older teens, and those with more severe symptoms took longer to respond. Why does this matter? It means if you've started therapy and medication together and don't feel different straight away, that's completely normal — the real magic of therapy often needs three months to show up properly. It's a good reminder to stick with treatment rather than giving up early. If you're struggling, reaching out to a psychologist or GP is a solid first step towards feeling better.
depressionteen depressionSSRICBT
Medication Plus Therapy: Why Patience Pays Off for Teen Depression
22 August 2026·1 min read
Plain-language summary · 1 min read